|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
MTHFR C677T and A1298C were not associated with preeclampsia (OR, 1.06; 95% CI, 0.97-1.16 and OR, 1.16; 95% CI, 0.97-1.39, respectively), and C677T was not associated with placental abruption (OR, 1.03; 95% CI, 0.87-1.21), intrauterine growth retardation (OR, 1.02; 95% CI, 0.90-1.15), or congenital heart disease (OR, 1.05; 95% CI, 0.89-1.25).
|
30474229 |
2019 |
|
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
MTHFR C677T and A1298C were not associated with preeclampsia (OR, 1.06; 95% CI, 0.97-1.16 and OR, 1.16; 95% CI, 0.97-1.39, respectively), and C677T was not associated with placental abruption (OR, 1.03; 95% CI, 0.87-1.21), intrauterine growth retardation (OR, 1.02; 95% CI, 0.90-1.15), or congenital heart disease (OR, 1.05; 95% CI, 0.89-1.25).
|
30474229 |
2019 |
|
rs1799963
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A combination of alleles G of rs1799963, A of rs6046, and G of rs1800790 (OR = 0.31) reduces the risk of FGR.
|
28544373 |
2017 |
|
rs1800790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A combination of alleles G of rs1799963, A of rs6046, and G of rs1800790 (OR = 0.31) reduces the risk of FGR.
|
28544373 |
2017 |
|
rs6046
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphism rs6046 of the FVII gene is associated with the development of FGR.
|
28544373 |
2017 |
|
rs587777736
|
|
G |
0.700 |
GeneticVariation |
CLINVAR |
Mutations in NOTCH1 cause Adams-Oliver syndrome.
|
25132448 |
2014 |
|
rs121918474
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found that protein S K196E mutation was identified in 4 out of 233 patients with recurrent miscarriage and in 2 out of 114 patients with FGR and/or IUFD.
|
24613695 |
2014 |
|
rs318240750
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified the novel c.836G>[G;T] (p.Arg279Leu) mutation in a familial case of intrauterine growth retardation (IUGR) with RSS phenotype and no evidence of IMAGe.
|
24065356 |
2013 |
|
rs1253103806
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Only the second compound heterozygous IGF1R mutations to be identified, the p.E121K/E234K variant is the cause of intrauterine growth retardation and the most severe postnatal growth failure described to date in a patient with IGF1R defects.
|
22130793 |
2012 |
|
rs187980012
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We identified a family bearing a new heterozygous missense mutation at the L2 domain of IGF-IR (R431L) through an 8-year-old girl and her mother, both born with intrauterine growth retardation.
|
22309212 |
2012 |
|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Our aim in this study was to investigate the association between elevated homocysteine levels and the two MTHFR polymorphisms, C677T and A1298C, with several pregnancy complications such as recurrent pregnancy loss, preeclampsia, placental abruption and intrauterine growth retardation.
|
21577095 |
2011 |
|
rs397507444
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our aim in this study was to investigate the association between elevated homocysteine levels and the two MTHFR polymorphisms, C677T and A1298C, with several pregnancy complications such as recurrent pregnancy loss, preeclampsia, placental abruption and intrauterine growth retardation.
|
21577095 |
2011 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results suggested a lack of association between the Glu298Asp gene polymorphism and pre-eclampsia without FGR in the Turkish population.
|
20598027 |
2010 |
|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The following number of related studies were found: studies evaluating relationships between factor V Leiden mutation and IUGR, 12 case-control and four cohort; between PT mutation and IUGR, 11 case-control and 0 cohort; and between MTHFR C677T homozygosity and IUGR, 10 case-control and two cohort.
|
19461414 |
2009 |
|
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The following number of related studies were found: studies evaluating relationships between factor V Leiden mutation and IUGR, 12 case-control and four cohort; between PT mutation and IUGR, 11 case-control and 0 cohort; and between MTHFR C677T homozygosity and IUGR, 10 case-control and two cohort.
|
19461414 |
2009 |
|
rs2536512
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Association of extracellular superoxide dismutase (SOD3) Ala40Thr gene polymorphism with pre-eclampsia complicated by severe fetal growth restriction.
|
19108943 |
2009 |
|
rs28937590
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A homozygous point mutation (232A-->G) has been found as the genetic etiology for fetal growth retardation, amino aciduria, cholestasis, iron overload, lactic acidosis, and early death (GRACILE) syndrome (MIM 603358).
|
18386115 |
2008 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, no significant differences were detected in the genotype, allele and haplotype frequencies of Asp299Gly and Thr399Ile TLR4 SNPs between patients with mild and severe preeclampsia, between patients with late and early onset of the disease, or between preeclamptic patients with and without fetal growth restriction.
|
18712040 |
2008 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Furthermore, no significant differences were detected in the genotype, allele and haplotype frequencies of Asp299Gly and Thr399Ile TLR4 SNPs between patients with mild and severe preeclampsia, between patients with late and early onset of the disease, or between preeclamptic patients with and without fetal growth restriction.
|
18712040 |
2008 |
|
rs1341667
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In an isolated Dutch population, a distortion could not be demonstrated in the transmission of STOX1-Y153H variation from heterozygous mothers to offspring in 50 and 56 families with pregnancies complicated by pre-eclampsia or intrauterine growth restriction, respectively.
|
17617193 |
2007 |
|
rs2297660
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The "A" allele at rs2297660 was associated with a higher standardized birth weight and a lower risk of FGR.
|
16642433 |
2006 |
|
rs1183194405
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single copy of a common polymorphism, Val34Leu in factor XIII, increased the risk of intrauterine growth restriction approximately 70% when the parent of origin was the father as opposed to the mother (p < 0.05).
|
16192348 |
2005 |
|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
No association was found in this study between intrauterine growth restriction with abnormal umbilical blood flow and thrombophilic polymorphisms or methylenetetrahydrofolate reductase C677T.
|
15075078 |
2004 |
|
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
No association was found in this study between intrauterine growth restriction with abnormal umbilical blood flow and thrombophilic polymorphisms or methylenetetrahydrofolate reductase C677T.
|
15075078 |
2004 |
|
rs1217691063
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Newborns who were homozygous for the MTHFR C677T variant had a decreased risk of intrauterine growth restriction (odds ratio after adjustment for mother's genotype and other confounders, 0.52 [95 percent confidence interval, 0.29 to 0.94]).
|
12097536 |
2002 |